منابع مشابه
Adverse Drug Effects
Differentiating between complicating consequences of HIV infection and toxicities of drugs used in the management of HIV infection is challenging. However, the experience gained with combination antiretroviral (ARV) drugs has led to the recognition of several distinct adverse drug events. These include: • mitochondrial dysfunction (including lactic acidosis, hepatic toxicity, pancreatitis, and ...
متن کاملAntiretroviral Drug Interactions and Adverse Side Effects
The complexity of antiretroviral therapy, coupled with the lifelong duration of treatment, presents the need for extensive management of drug interactions and adverse effects. This article includes an extensive discussion of drug interactions involving antiretroviral agents and other medications (eg, antibiotics, oral contraceptives, H2 antagonists, and lipid-lowering agents) commonly used in i...
متن کاملAdverse Metabolic Effects of Antiepileptic Drug Treatment
Active epilepsy with recurrent seizures is associated with a range of well-documented unfavourable consequences. Nevertheless, adverse metabolic effects of antiepileptic drug (AED) treatments have only recently received attention. Such effects may be subtle, insidious, take many years to become clinically apparent, and may have a negative impact on general health for many decades. Unfortunately...
متن کاملDrug Substance and Drug Product Impurities, Now what?
An unidentified peak in a drug substance or drug product chromatogram raises many questions. What is the impurity? What is the source of the impurity? How much impurity is there? Can the impurity level be reduced or eliminated? Is the impurity toxic? What do we do now? The answers to these questions are typically provided by scientists in chemistry, manufacturing and controls (CMC) and nonclini...
متن کامل3-Adrenergic Receptor Blockers Adverse Effects and Drug Interactions
Adverse effects of /3-adrenergic receptor blocking drugs can be divided into two categories: 1) those that result from known pharmacological consequences of /3-adrenergic receptor blockade; and 2) other reactions that do not appear to result from /3-adrenergic receptor blockade. Adverse effects of the first type include bronchospasm, heart failure, prolonged hypoglycemia, bradycardia, heart blo...
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ژورنال
عنوان ژورنال: Indian Journal of Psychological Medicine
سال: 1998
ISSN: 0253-7176,0975-1564
DOI: 10.1177/0975156419980107